LP16744-2
Zidovudine
Active
Descriptions
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. Source: National Library of Medicine, MeSH 2006
Zidovudine is a Nucleoside Reverse Transcriptase Inhibitor(NRTI) antiretroviral drug used in the treatment of HIV. Drug resistance reports assist with treatment decisions. Source: Regenstrief Institute
Zidovudine (INN) or azidothymidine (AZT) (also called ZDV) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the first clinically proven successful treatment of HIV/AIDS infectiousness. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Zidovudine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Zidovudine
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP16744-2 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP16744-2
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 齐多夫定 Synonyms: AZT; |
| fr-CA | French (Canada) | Zidovudine |
| et-EE | Estonian (Estonia) | Tsidovudiin |
| es-ES | Spanish (Spain) | Zidovudina |
| it-IT | Italian (Italy) | Zidovudina |
| tr-TR | Turkish (Turkey) | Zidovudine |
| ru-RU | Russian (Russian Federation) | Зидовудин |
| nl-NL | Dutch (Netherlands) | zidovudine |
| fr-BE | French (Belgium) | Zidovudine |
LOINC Copyright
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