Version 2.78

Descriptions

Ceftaroline fosamil (INN) (pron.: /sɛfˈtærɵliːn/), brand name Teflaro, is an advanced-generatio cephalosporin antibiotic. It is active against methicillin-resistant Staphylococcus aureus (MRSA) and Gram-positive bacteria. It retains the activity of later-generation cephalosporins having broad-spectrum activity against Gram-negative bacteria. It is currently being investigated for community-acquired pneumonia and complicated skin and skin structure infection. Ceftaroline is being developed by Forest Laboratories, under a license from Takeda. Ceftaroline has received approval from the U.S. Food and Drug Administration for the treatment of community-acquired bacterial pneumonia and acute bacterial skin infections on October 29, 2010. In vitro studies show that it has a similar spectrum to ceftobiprole, the only other fifth-generation cephalosporin to date, although no head to head clinical trials have been conducted. Currently, ceftaroline and ceftobiprole are on an unnamed subclass of cephalosporins by the Clinical and Laboratory Standards Institute (CLSI). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Ceftaroline

The activity of ceftaroline is broadened to include beta lactamase producing gram negative bacteria by the addition of avibactam. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Ceftaroline+Avibactam
Part Type
Component (Describes the core component or analyte measured)
Created On
2013-01-30
Construct for LOINC Short Name
Ceftaroline+Avibactam

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP172559-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 头孢洛林+阿维巴坦
Synonyms: 头孢洛林(头孢洛林酯、头孢他诺林、头孢他洛林酯、头孢他洛林)+阿维巴坦;阿维巴坦;NXL-104;二氮杂双环辛酮化合物;非β-内酰胺类抑制剂;CAS 1192500-31-4;C7H11N3O6S;硫酸单[(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-氮杂双环[3.2.1]辛-6-基]酯;Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester
es-ES Spanish (Spain) Ceftarolina+Avibactam
it-IT Italian (Italy) Ceftarolina+Avibactam
tr-TR Turkish (Turkey) Seftarolin+Avibaktam
ru-RU Russian (Russian Federation) Цефтаролин+Авибактам
nl-NL Dutch (Netherlands) ceftaroline + avibactam