LP172734-8
Transaldolase
Active
Description
Transaldolase is an enzyme of the non-oxidative phase of the pentose phosphate pathway, which has two metabolic functions: (1) generation of nicotinamide adenine dinucleotide phosphate (reduced NADPH), for reductive biosynthesis, and (2) formation of ribose which is an essential component of ATP, DNA, and RNA. Transaldolase links the pentose phosphate pathway to glycolysis. In patients with deficiency of transaldolase, there's an accumulation of erythritol (from erythrose 4-phosphate), D-arabitol, and ribitol. In humans, transaldolase is encoded by the TALDO1 gene. A deletion in 3 base pair at position 171 of the transaldolase protein results in a mutation that causes the transaldolase deficiency found in erythrocytes and lymphoblasts. The deletion can lead to liver cirrhosis and hepatosplenomegaly (enlarged spleen and liver) during early infancy. Transaldolase is also a target of autoimmunity in patients with multiple sclerosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Transaldolase
Basic Part Properties
- Part Name
- Transaldolase
- Part Display Name
- Transaldolase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2013-03-06
- Construct for LOINC Short Name
- Transaldolase
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 转醛醇酶 Synonyms: 转醛酶; |
| es-ES | Spanish (Spain) | Transaldolasa |
| it-IT | Italian (Italy) | Transaldolasi |
| tr-TR | Turkish (Turkey) | Transaldolaz |
| ru-RU | Russian (Russian Federation) | Трансальдолаза |
| nl-NL | Dutch (Netherlands) | transaldolase |
| fr-FR | French (France) | Transaldolase |
| el-GR | Greek (Greece) | Τρανσαλδολάση Synonyms: Τρανσαλδολάση |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://