LP17857-1
Baclofen
Active
Descriptions
A gamma-aminobutyric acid derivative that is a specific agonist at GABA-B receptors (receptors, GABA-B). It is used in the treatment of spasticity, especially that due to spinal cord damage. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. Source: National Library of Medicine, MeSH 2006
Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Beklo and Baclosan) is a derivative of gamma-aminobutyric acid (GABA) and acts as an agonist for the GABA-B receptors. It is primarily used to treat spasticity. It has also been used to treat symptoms of opiate withdrawl, including muscle cramps and muscle pain as well as the intense shivering often experienced. Research has shown it may be an effective treatment for alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings. Oral dosage must be carefully regulated; significantly high doses of the drug, particularly 80 mg per day or higher, can cause excessive ataxia and/or drowsiness that can interfere with daily function. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Baclofen
Basic Part Properties
- Part Display Name
- Baclofen
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Baclofen
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 巴氯芬 Synonyms: 力奥来素; |
| fr-CA | French (Canada) | Baclofène |
| et-EE | Estonian (Estonia) | Baklofeen |
| es-ES | Spanish (Spain) | Baclofeno |
| it-IT | Italian (Italy) | Baclofene |
| tr-TR | Turkish (Turkey) | Baklofen |
| ru-RU | Russian (Russian Federation) | Баклофен |
| nl-NL | Dutch (Netherlands) | baclofen |
| fr-BE | French (Belgium) | Baclofene |
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