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Description

9-Hydroxyrisperidone, also called paliperidone, is an active metabolite of risperidone and is itself a prescribable atypical antipsychotic. Although 9-Hydroxyrisperidone is a metabolite of risperidone, they have several important differences including serotonin 5-HT2A and dopamine D2 receptor binding, and ability to cross the blood brain barrier (BBB). Risperidone has a significantly lower 5-HT2A/D2 binding ratio and crosses the BBB more effectively. Both drugs are used to treat schizophrenia and other related disorders. PMID: 25943458 Source: Regenstrief LOINC

Basic Part Properties

Part Name
9-Hydroxyrisperidone
Part Display Name
9-Hydroxyrisperidone
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
9OH-risperidone

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP17865-4
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP17865-4

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)9-羟基利培酮
Synonyms: 利培酮代谢物;利培酮代谢产物;9-羟利培酮;帕潘立酮;6,7,8,9-四氢-3-(2-(4-(6-氟-1,2-苯并异恶唑-3-基)-1-哌啶基)乙基)-9-羟基-2-甲基-4H-吡啶并[2,1-a]嘧啶-4-酮;Paliperidone;INVEGA;INVEGA Sustenna;9-Hydroxyrisperidone;6,7,8,9-Tetrahydro-3-(2-(4-(6-fluro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-9-hydroxy-2-
fr-CAFrench (Canada)9-hydroxyrispéridone
et-EEEstonian (Estonia)9-hüdroksürisperidoon
es-ESSpanish (Spain)9-Hidroxirisperidona
it-ITItalian (Italy)9-Idrossirisperidone
tr-TRTurkish (Turkey)9-Hidroksirisperidon
ru-RURussian (Russian Federation)9-Гидроксирисперидон
nl-NLDutch (Netherlands)9-hydroxyrisperidon
fr-BEFrench (Belgium)9-hydroxyrispéridone
fr-FRFrench (France)9-hydroxyrispéridone
pl-PLPolish (Poland)9-Hydroksyrisperidon
Synonyms: 9-Hydroksyrysperydon
el-GRGreek (Greece)9-υδροξυ-ρισπεριδόνη
Synonyms: 9-υδροξυ-ρισπεριδόνη