LP18271-4
Complement Sc5b-9
Active
Description
The complement terminal complement complex (TCC) is comprised of complements C5b, C6, C7, C8, and C9 (C5b-9) and is a marker of complement activation. There are two forms of TCC: 1. Soluble TCC is formed when C5b-7 that is not associated with a lipid membrane binds to C8 and C9. SC5b-9 is soluble TCC that is bound to a plasma protein such as S-protein (vitronectin) or clusterin. Plasma SC5b-9 is the non-functional form of C5b-9 and is a non-specific marker of complement activation and inflammation.; 2. The membrane attack complex (MAC), a barrel-like structure spanning a cell's lipid bilayer that mediates complement cytotoxicity, is formed when C8 and C9 bind to C5b-7 that is already associated with a membrane, and is the functional form of C5b-9. PMID: 27782334 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Complement Sc5b-9
- Part Display Name
- Complement Sc5b-9
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- SC5b9
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 补体 Sc5b-9 Synonyms: 终末补体复合体（Terminal complement complex）; |
| es-ES | Spanish (Spain) | Complemento Sc5b-9 |
| it-IT | Italian (Italy) | Complemento Sc5b-9 |
| tr-TR | Turkish (Turkey) | Kompleman Sc5b-9 |
| ru-RU | Russian (Russian Federation) | Комплемент Sc5b-9 |
| fr-BE | French (Belgium) | Complément Sc5b-9 |
| fr-CA | French (Canada) | Complément Sc5b-9 |
| nl-NL | Dutch (Netherlands) | complement Sc5b-9 |
| el-GR | Greek (Greece) | Συμπλήρωμα Sc5b-9 Synonyms: Συμπλήρωμα Sc5b-9 |
LOINC Copyright
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