LP18330-8

Duffy group

Active

Description

The Duffy genes, located on chromosome one at position 1922-23, have recently been cloned and sequenced. The difference between Fy^a and Fy^b is a change in the amino acid at position 43 from aspartic acid (Fy^a) to glycine (Fy^b). Studies have shown that blacks whose erythrocytes express Fy^b antigen also have the antigen on the cells of their kidney, heart, muscle, brain and placenta. The Duffy gene codes for a protein known as a chemokine receptor, which is important in the inflammatory process. Accordingly, the Fy protein is also known as DARC (Duffy Antigen Receptor for Chenokines). Source: Serum, Cells and Rare Fluid Exchange, Duffy group

Basic Part Properties

Part Name

Duffy group

Part Display Name

Duffy group

Part Type

Component (Describes the core component or analyte measured)

Created On

2000-05-04

Construct for LOINC Short Name

Duffy Group

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