LP183573-7

Basophils.CD63

Active

Description

Activation of basophilic granulocytes with anti-IgE and the expression of the CD63 antigen on the cell surface allows identification of an allergy. Basophiles, along with mast cells, are considered to be the key cells in allergic diseases. Hypersensitivity reactions are caused by an initial systemic histamine release by activated basophiles and mast cells, which may lead to shock with laryngeal edema, lower-airway obstruction and hypotension. The index method for this test establishes the basophil population by use of low SSC (side scatter) and a human chemokine receptor CCR3 marker. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Basophil activation

Basic Part Properties

Part Name

Basophils.CD63

Part Display Name

CD63 Basophils

Part Type

Component (Describes the core component or analyte measured)

Created On

2014-03-28

Construct for LOINC Short Name

CD63 Basophils

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