Version 2.80

Description

The HNF4A gene (hepatocyte nuclear factor 4, alpha) [HGNC Gene ID:5024] is located on chromosome 20q13.12. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] [NCBI Gene ID:3172] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
HNF4A gene
Part Display Name
HNF4A gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2014-07-10
Construct for LOINC Short Name
HNF4A

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185371-4

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen HNF4A
zh-CN Chinese (China) HNF4A 基因
Synonyms: 肝细胞核因子 4 alpha;肝细胞核因子 4α;Hepatocyte nuclear factor 4 alpha;核受体亚家族 2, 组 A, 成员 1;核受体亚家族 2, A 组, 成员 1;nuclear receptor subfamily 2, group A, member 1;转录因子 14;transcription factor 14;HNF4A;HNF4;HNF4a7;HNF4a8;HNF4a9;HNF4alpha;MODY;MODY1;NR2A1;NR2A21;TCF;TCF14
it-IT Italian (Italy) HNF4A, gene
Synonyms: Gene HNF4A
tr-TR Turkish (Turkey) HNF4A geni
nl-NL Dutch (Netherlands) HNF4A-gen
Synonyms: HNF4A gen
el-GR Greek (Greece) Γονίδιο HNF4A
Synonyms: Γονίδιο HNF4A