LP185373-0
GCDH gene
Active
Description
The GCDH gene (glutaryl-CoA dehydrogenase) [HGNC Gene ID:4189] is located on chromosome 19p13.2. The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013] [NCBI Gene ID:2639] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- GCDH gene
- Part Display Name
- GCDH gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2014-07-11
- Construct for LOINC Short Name
- GCDH
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | GCDH 基因 Synonyms: 戊二酰辅酶 A 脱氢酶基因; |
| es-ES | Spanish (Spain) | Gen GCDH |
| it-IT | Italian (Italy) | GCDH, gene Synonyms: Gene GCDH |
| tr-TR | Turkish (Turkey) | GCDH geni |
| nl-NL | Dutch (Netherlands) | GCDH-gen Synonyms: GCDH gen |
| fr-FR | French (France) | GCDH gène |
| pl-PL | Polish (Poland) | GCDH gen Synonyms: Gen GCDH |
| el-GR | Greek (Greece) | Γονίδιο GCDH Synonyms: Γονίδιο GCDH |
LOINC Copyright
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