LP18567-5
Estrogen receptor
Active
Description
Estrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding.
Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Estrogen receptor
Basic Part Properties
- Part Name
- Estrogen receptor
- Part Display Name
- Estrogen receptor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ER
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 雌激素受体 Synonyms: ER; |
| fr-CA | French (Canada) | Récepteur de l'œstrogène |
| et-EE | Estonian (Estonia) | Östrogeeni retseptor |
| es-ES | Spanish (Spain) | Receptor de estrógeno |
| it-IT | Italian (Italy) | Estrogeno, recettore Synonyms: Recettore degli estrogeni |
| tr-TR | Turkish (Turkey) | Östrojen reseptörü |
| ru-RU | Russian (Russian Federation) | Эстроген рецептор Synonyms: Рецептор к эстрогену |
| nl-NL | Dutch (Netherlands) | oestrogeenreceptor |
| fr-BE | French (Belgium) | Récepteur d'œstrogène Synonyms: Récepteur d''oestrogènes |
| fr-FR | French (France) | Estrogènes récepteurs |
| pl-PL | Polish (Poland) | Receptor estrogenowy Synonyms: ER |
| el-GR | Greek (Greece) | Υποδοχέας οιστρογόνων Synonyms: Υποδοχέας οιστρογόνων |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://