Description

Chorionic villus sampling (CVS) and amniocentesis are two methods for invasive prenatal screening and diagnosis for the fetus. CVS is usually performed during the first trimester, between 10 and 13 weeks' gestation, by using ultrasound guidance to obtain a sample of placental villi using either a transcervical or transabdominal approach. Amniocentesis is typically performed during the second trimester, between 15 and 20 weeks' gestation, using ultrasound guidance to obtain a sample of amniotic fluid. The rate of procedure-related pregnancy loss from both CVS and second trimester amniocentesis has decreased over time and is approximately 0.1-0.3% in procedures performed by experienced health care providers. Early amniocentesis, performed before 14 weeks' gestation, is associated with a higher rate of pregnancy loss, other complications, and fluid culture failures, and therefore is not recommended. Both CVS and amniocentesis samples can be used for methods that target chromosome- and gene-level variation, as well as for mitochondrial, enzyme and other biochemical analysis for the fetus. Results based on CVS and amniotic fluid samples are expected to be the same, with the exception of open neural tube defects as described below. The main advantage of CVS compared to amniocentesis is that the procedure can be performed earlier in pregnancy and the specimen processing time is shorter for the viable cells obtained by CVS, which allows earlier diagnosis and therefore more time to consider options for management. PMID: 26938573 However, CVS cannot detect open neural tube defects, while amniocentesis can detect certain ones, including spina bifida and anencephaly. PMID: 19915395 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Amnio fld/CVS
Part Display Name
Amniotic fluid or Chorionic villus sample
Part Type
System (Describes the name of the system (sample) type)
Created On
2014-08-11
Construct for LOINC Short Name
Amn/CVS

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185743-4

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)羊水/绒毛膜绒毛样本
Synonyms: 羊水(羊膜水、胎水)或绒毛膜绒毛样本(绒毛膜绒毛标本、绒膜绒毛标本、绒膜绒毛样本、CVS)
es-ESSpanish (Spain)Líquido amniótico o muestra de vellosidades coriónicas
it-ITItalian (Italy)Liquido amniotico/Villi coriali, prelievo
Synonyms: Prelievo del liquido amniotico o dei villi coriali
tr-TRTurkish (Turkey)Amnio sv/CVS
fr-FRFrench (France)Liquide amniotique/Villosités choriales
pl-PLPolish (Poland)próbka płynu owodniowego lub kosmka kosmówki
el-GRGreek (Greece)Αμνιακό υγρό/ΕΝΥ
Synonyms: Αμνιακό υγρό/ΕΝΥ