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Description

Cell-free DNA (cfDNA) is DNA that circulates in the plasma, and in pregnant women, cfDNA is both maternal and fetal in origin. Fetal cfDNA can be detected in maternal plasma as early as 7 weeks' gestation and the proportion of fetal cfDNA increases during the pregnancy. Fetal cfDNA is continuously added to maternal circulation and is cleared within hours. Certain noninvasive prenatal screening tests analyze maternal cfDNA to determine the fetal risk for a variety of genetic disorders. The proportion of cfDNA, calculated as fetal cfDNA/total cfDNA and also known as fetal fraction, is one of the reported measures, and in general, samples with a higher fetal fraction yield more sensitive results than those with lower fetal fraction. PMID: 24466384 Source: Regenstrief LOINC, PMID: 24466384

Basic Part Properties

Part Name
Cell-free DNA.fetal
Part Display Name
Cell-free DNA.fetal
Part Type
Component (Describes the core component or analyte measured)
Created On
2014-09-04
Construct for LOINC Short Name
cfDNA.fet

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185863-0

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)cfDNA.胎儿
Synonyms: 胎儿血浆循环 cfDNA;胎儿血浆循环 DNA;胎儿循环游离核酸;胎儿血浆游离 DNA;胎儿血浆无细胞 DNA;Fetal free circulating/cell-free DNA;Fetal free circulating DNA
es-ESSpanish (Spain)ADN fetal libre de células
it-ITItalian (Italy)DNA libero circolante.fetale
Synonyms: DNA fetale libero circolante
tr-TRTurkish (Turkey)Hücresiz DNA.fetal
nl-NLDutch (Netherlands)cel-vrij DNA.foetaal
fr-FRFrench (France)ADN libre fœtal
pl-PLPolish (Poland)Wolnokrążące DNA.płód
Synonyms: cffDNA;wolnokrążące DNA płodu
el-GRGreek (Greece)DNA χωρίς κύτταρα.εμβρυϊκό
Synonyms: DNA χωρίς κύτταρα.εμβρυϊκό