LP185940-6
HTR2A gene.c.-1438G>A
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Description
Antidepressant and antipsychotic medication selection may be determined based on a patient's genotype for various polymorphisms within the HTR2A and HTR2C genes, which encode the serotonin (5-hydroxytryptamine) receptors HTR2A and HTR2C. PMID: 15121641 Variants in HTR2A, for example c.102T>C and c.-1438G>A, have been found to affect response to selective serotonin reuptake inhibitors (SSRI) and risk for adverse drug reactions as well as response to the antipsychotic drugs clozapine and aripiprazole. PMID: 14514498, PMID: 10821369 Patients treated with antipsychotics and having significant weight gain have been positively correlated with a polymorphism in the promoter region of HTR2C, c.759C>T, where those with the -759T variant allele showed significantly less weight gain than those without this allele. PMID: 12668355 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- HTR2A gene c.-1438G>A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2014-09-17
- Construct for LOINC Short Name
- HTR2A c.-1438G>A
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | HTR2A 基因.c.-1438G>A |
| es-ES | Spanish (Spain) | Gen HTR2A c.-1438G>A |
| it-IT | Italian (Italy) | HTR2A, gene.c.-1438G>A Synonyms: Gene HTR2A c.-1438G>A |
| tr-TR | Turkish (Turkey) | HTR2A geni.c.-1438G>A |
| nl-NL | Dutch (Netherlands) | HTR2A-gen.c.-1438G>A Synonyms: HTR2A gen.c.-1438G>A |
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