LP18858-8
CD28
Active
Description
CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for B7.1 (CD80) and B7.2 (CD86). When activated by Toll-like receptor ligands, the B7.1 expression is upregulated in antigen presenting cells (APCs). The B7.2 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Stimulation through CD28 in addition to the TCR can provide a potent co-stimulatory signal to T cells for the production of various interleukins (IL-2 and IL-6 in particular).
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Source: Wikipedia,
CD28
Basic Part Properties
- Part Name
- CD28
- Part Display Name
- CD28
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- CD28
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD28 Synonyms: T44; |
| es-ES | Spanish (Spain) | CD28 |
| it-IT | Italian (Italy) | CD28 |
| tr-TR | Turkish (Turkey) | CD28 |
| ru-RU | Russian (Russian Federation) | CD28 |
| nl-NL | Dutch (Netherlands) | CD28 |
| pl-PL | Polish (Poland) | CD28 Synonyms: CD28 |
| el-GR | Greek (Greece) | CD28 Synonyms: CD28 |
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