LP189378-5

PLOD3 gene

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Description

The PLOD3 gene (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3) [HGNC Gene ID:9083] is located on chromosome 7q22. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008] [NCBI Gene ID:8985] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name: PLOD3 gene
Part Display Name: PLOD3 gene
Part Type: Component (Describes the core component or analyte measured)
Created On: 2015-02-04
Construct for LOINC Short Name: PLOD3

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CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP189378-5

Language Variants Get Info

Tag	Language	Translation
zh-CN	Chinese (China)	PLOD3 基因 Synonyms: 前胶原-赖氨酸, 2-酮戊二酸 5-双加氧酶 3;前胶原-赖氨酸, 2-酮戊二酸 5-加双氧酶 3;前胶原-赖氨酸, 2-酮戊二酸 5-二氧酶 3;Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3
es-ES	Spanish (Spain)	Gen PLOD3
it-IT	Italian (Italy)	PLOD3, gene Synonyms: Gene PLOD3
tr-TR	Turkish (Turkey)	PLOD3 geni
nl-NL	Dutch (Netherlands)	PLOD3-gen Synonyms: PLOD3 gen
fr-FR	French (France)	PLOD3 gène
pl-PL	Polish (Poland)	PLOD3 gen Synonyms: Gen PLOD3
el-GR	Greek (Greece)	Γονίδιο PLOD3 Synonyms: Γονίδιο PLOD3

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