LP19063-4
Cells.CD45RO
Active
Description
CD45 (also known as leukocyte common antigen) is a tyrosine phosphatase specific to hematopoietic cells that is necessary for efficient T and B cell antigen receptor signal transduction. Multiple CD45 isoforms can be generated by alternative splicing of the A, B and C extracellular domains. In humans, naive T lymphocytes express CD45RA, which includes the A domain, and activated T lymphocytes express CD45RO, which does not contain A, B or C. PMID: 16423560 CD45RB and RC are not as well-understood in humans as CD45RA and RO, but peripheral T cells that express CD45RA have also been found to express high levels of CD45RB, whereas CD45RO cells do not PMID: 15020649, and high levels of CD45RC expression on CD8+ T cells may be predictive of acute kidney graft rejection in transplant patients. PMID: 23894540 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Cells.CD45RO
- Part Display Name
- CD45RO cells
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- CD45RO Cells
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 细胞.CD45RO Synonyms: CD45RO细胞 |
| es-ES | Spanish (Spain) | Células CD45RO |
| it-IT | Italian (Italy) | Cellule.CD45RO Synonyms: Cellule CD45RO |
| et-EE | Estonian (Estonia) | Rakud.CD45RO |
| tr-TR | Turkish (Turkey) | Hücreler.CD45RO |
| ru-RU | Russian (Russian Federation) | Клетки.CD45RO |
| fr-BE | French (Belgium) | Cellules.CD45RO |
| fr-CA | French (Canada) | Cellules.CD45RO |
| nl-NL | Dutch (Netherlands) | cellen.CD45RO |
| pl-PL | Polish (Poland) | Komórki.CD45RO Synonyms: Komórki CD45RO |
| el-GR | Greek (Greece) | Κύτταρα.CD45RO Synonyms: Κύτταρα.CD45RO |
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