Description

CD45 (also known as leukocyte common antigen) is a tyrosine phosphatase specific to hematopoietic cells that is necessary for efficient T and B cell antigen receptor signal transduction. Multiple CD45 isoforms can be generated by alternative splicing of the A, B and C extracellular domains. In humans, naive T lymphocytes express CD45RA, which includes the A domain, and activated T lymphocytes express CD45RO, which does not contain A, B or C. PMID: 16423560 CD45RB and RC are not as well-understood in humans as CD45RA and RO, but peripheral T cells that express CD45RA have also been found to express high levels of CD45RB, whereas CD45RO cells do not PMID: 15020649, and high levels of CD45RC expression on CD8+ T cells may be predictive of acute kidney graft rejection in transplant patients. PMID: 23894540 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Cells.CD45RO
Part Display Name
CD45RO cells
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
CD45RO Cells

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP19063-4

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)细胞.CD45RO
Synonyms: CD45RO细胞
fr-CAFrench (Canada)Cellules.CD45RO
et-EEEstonian (Estonia)Rakud.CD45RO
es-ESSpanish (Spain)Células CD45RO
it-ITItalian (Italy)Cellule.CD45RO
Synonyms: Cellule CD45RO
tr-TRTurkish (Turkey)Hücreler.CD45RO
ru-RURussian (Russian Federation)Клетки.CD45RO
nl-NLDutch (Netherlands)cellen.CD45RO
fr-BEFrench (Belgium)Cellules.CD45RO
fr-FRFrench (France)CD45RO
pl-PLPolish (Poland)Komórki.CD45RO
Synonyms: Komórki CD45RO
el-GRGreek (Greece)Κύτταρα.CD45RO
Synonyms: Κύτταρα.CD45RO