LP190749-4
Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
Active
Description
The M. abscessus complex consists of three subspecies (M. abscessus subsp. Abscessus, M. abscessus subsp. Massiliense, M. abscessus subsp. Bolletii). PMID: 22403419 They are known to cause respiratory disease in cystic fibrosis and elderly patients as well as skin and soft tissue infections. PMID: 25106861 M. abscessus infections are often difficult to treat as many strains are resistant to most of the common antibiotics. Their resistance to clarithromycin can be determined based on expression of the inducible ribomethylase gene, erm(41). The presence of a full length functional erm(41)gene, which is specific for M. abscessus, confers inducible resistance to clarithromycin while the non-functional truncated erm(41) gene exhibits higher drug susceptibility. PMID: 22290346 Real-time PCR methods are performed to detect the presence of the full or truncated erm(41) gene and determine proper treatment for patients. Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
- Part Display Name
- Mycobacterium abscessus complex clarithromycin resistance erm(41) gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-04-28
- Construct for LOINC Short Name
- M abscessus erm(41)
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP190749-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 脓肿分枝杆菌复合体克拉霉素耐药 erm(41) 基因 Synonyms: 脓肿分枝杆菌（脓肿分支杆菌、 |
| es-ES | Spanish (Spain) | Mycobacterium abscessus complex resistente a claritromicina (erm(41)) gen |
| it-IT | Italian (Italy) | Complesso Mycobacterium abscessus claritromicina resistente, gene (erm(41)) |
| tr-TR | Turkish (Turkey) | Mycobacterium abscessus kompleks klaritromicsin dirençli (erm(41)) geni |
| nl-NL | Dutch (Netherlands) | Mycobacterium abscessus complex clarithromycine-resistent (erm(41)) gen |
LOINC Copyright
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