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Description

The ANG gene (angiogenin, ribonuclease, RNase A family, 5) [HGNC Gene ID: 483] is located on chromosome 14q11.1-q11.2.The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014][NCBI Gene ID: 283] Mutations in ANG gene cause the Amyotrophic lateral sclerosis 9 phenotype.[OMIM: 105850] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
ANG gene
Part Display Name
ANG gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-04-30
Construct for LOINC Short Name
ANG gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP190762-7

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)ANG 基因
Synonyms: 血管生成素（血管生长素）, 核糖核酸酶（ RNA 酶）, RNase A 家族, 5;核糖核酸酶 5;附睾管腔蛋白（附睾腔蛋白） 168;核糖核酸酶 A A1;血管生成素;Angiogenin, Ribonuclease, RNase A Family, 5;Ribonuclease 5;RNase 5;Epididymis Luminal Protein 168;Ribonuclease A A1;EC 3.1.27.-;Angiogenin;EC 3.1.27;HEL168;RNASE4;RAA1;R
es-ESSpanish (Spain)Gen ANG
it-ITItalian (Italy)ANG, gene
Synonyms: Gene ANG
tr-TRTurkish (Turkey)ANG geni
nl-NLDutch (Netherlands)ANG-gen
Synonyms: ANG gen
fr-FRFrench (France)ANG gène
pl-PLPolish (Poland)ANG gen
Synonyms: Gen ANG
el-GRGreek (Greece)Γονίδιο ANG
Synonyms: Γονίδιο ANG