LP193317-7
Factor VIII+von Willebrand factor.ristocetin cofactor
Active
Description
Von Willebrand factor (vWF) is a high-molecular-weight plasma protein produced by endothelial cells and megakaryocytes. It is part of the factor VIII/vWF complex. The vWF has receptors for collagen, platelets, and ristocetin. Ristocetin is an antibiotic, previously used to treat staphylococcal infections, now mainly used in vitro to diagnose conditions such as von Willebrand disease. Platelet agglutination caused by ristocetin can occur only in the presence of von Willebrand factor multimers, so if ristocetin is added to blood lacking the factor it will not coagulate. The vWF facilitates the adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in von Willebrand's disease is due to the deficiency of this factor. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Name
- Factor VIII+von Willebrand factor.ristocetin cofactor
- Part Display Name
- Factor VIII+von Willebrand factor (vWf) ristocetin cofactor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-06-09
- Construct for LOINC Short Name
- FVIII+vWf:RCo
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 凝血因子 VIII+von Willebrand 因子.瑞斯托菌素辅助因子 Synonyms: 凝血因子 VIII（凝血因子Ⅷ、 |
| es-ES | Spanish (Spain) | Factor VIII+Factor Von Willebrand cofactor ristocetina |
| it-IT | Italian (Italy) | Fattore VIII+Fattore di von Willebrand.cofattore ristocetina Synonyms: Fattore VIII+Cofattore ristocetina del Fattore di |
| tr-TR | Turkish (Turkey) | Faktör VIII+von Willebrand faktörü.ristosetin kofaktörü |
| nl-NL | Dutch (Netherlands) | factor VIII + von Willebrand-factor.ristocetine cofactor |
| fr-FR | French (France) | Factor VIII+cofacteur ristocétine du facteur Willebrand |
| pl-PL | Polish (Poland) | Czynnik VIII+czynnik von Willebranda aktywność kofaktora rystocetyny |
| el-GR | Greek (Greece) | Παράγοντας VIII+παράγοντας Von Willebrand.συμπαράγοντας ριστοσετίνης Synonyms: Παράγοντας VIII+παράγοντας Von Willebrand.συμπαράγοντας ριστοσετίνης |
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