LP19557-5
Transferrin.carbohydrate deficient.trisialo
Active
Description
Carbohydrate-deficient transferrin (CDT) are transferrin glycoproteins that have decreased or absent sialic acid residues and reduced numbers of oligosaccharide chains. Transferrin (Tf) normally has two N-linked oligosaccharide chains with two sialic acid residues each, so exists primarily in the tetra-sialo isoform. Forms of CDT include the tri-sialo form, with three instead of four sialic residues, and di-sialo, with two sialic acid residues. The hyposialylation or desialylation of transferrin is associated with congenital disorders of glycosylation (CDG), alcohol abuse, fructosemia, and galactosemia. Tf is the most prevalent and studied glycoprotein, and the evaluation of its isoforms is one of the screening assays used to rule out CDG. Manifestations of CDG are widely variable and can range from severe retardation with dysmorphic physical features, to mild retardation or no detectable symptoms. PMID: 28236367 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Transferrin.carbohydrate deficient.trisialo
- Part Display Name
- Transferrin.carbohydrate deficient.trisialo
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- CDT Trisialo
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 转铁蛋白.碳水化合物缺乏性.三唾液酸 Synonyms: 转铁蛋白.碳水化合物缺乏性.三唾液酸成分; |
| es-ES | Spanish (Spain) | Transferrina deficiente en carbohidratos, fracción trisialotransferrina |
| it-IT | Italian (Italy) | Transferrina.carboidrato deficiente.frazione trisialo Synonyms: Transferrina carboidrato carente, frazione trisial |
| et-EE | Estonian (Estonia) | Transferriin.süsivesikdefitsiitne.trisialo-fraktsioon |
| tr-TR | Turkish (Turkey) | Transferrin.karbonhidrat yetmezliği.trisiyalo fraksiyonu |
| ru-RU | Russian (Russian Federation) | Трансферрин.углевод-дефицитный.трисиало фракция Synonyms: Трансферрин.углеводами бедный.трисиало фракция |
| fr-BE | French (Belgium) | Transferrine.déficiente.fraction trisialo- Synonyms: CDT. Trisialo |
| fr-CA | French (Canada) | Transferrine.déficiente en carbohydrates.trisialo |
| nl-NL | Dutch (Netherlands) | transferrine.koolhydraatdeficiënt.trisialo Synonyms: transferrine.carbohydraat deficient.trisialo fractie |
| el-GR | Greek (Greece) | Τρανσφερρίνη.ανεπάρκεια υδατανθράκων.τρισιάλο Synonyms: Τρανσφερρίνη.ανεπάρκεια υδατανθράκων.τρισιάλο |
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