Version 2.78

Description

The NB gene (NME/NM23 nucleoside diphosphate kinase 1) gene is located on chromosome 17q21.3. This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4830] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

Type Source Reference
Webcontent Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. Link to OMIM

Basic Part Properties

Part Name
NB gene
Part Display Name
NB gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
NB gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP19746-4
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP19746-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) NB 基因
Synonyms: NBS 基因;成神经细胞瘤抑制因子基因;成神经细胞瘤抑制基因;成神经细胞瘤抑制蛋白基因
et-EE Estonian (Estonia) NB geen
es-ES Spanish (Spain) Gen NB
it-IT Italian (Italy) NB, gene
Synonyms: Gene NB
tr-TR Turkish (Turkey) NB geni
ru-RU Russian (Russian Federation) NB ген
nl-NL Dutch (Netherlands) NB-gen
Synonyms: NB gen