LP19781-1
TCRB gene rearrangements
Active
Descriptions
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is, in general, responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules.
The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) chain (TCRA gene) and beta (β) chain (TCRB gene), whereas in 5% of T cells this consists of gamma (γ) chain (TCRG gene) and delta (δ) chain (TCRD gene).
When the TCR engages with antigen and MHC, this activates the T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors, specialized accessory molecules and activated or released transcription factors.
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Source: Wikipedia,
wikipedia
Associated with human lymphoid leukemias Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- TCRB gene rearrangements
- Part Display Name
- TCRB gene rearrangements
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- TCRB gene Rear
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | TCRB 基因重排 Synonyms: TCRB 基因重排（重组）; |
| et-EE | Estonian (Estonia) | TCRB geeni muudatused |
| es-ES | Spanish (Spain) | Reordenamientos del gen TCRB |
| it-IT | Italian (Italy) | TCRB, riarrangiamenti gene Synonyms: Riarrangiamenti di gene del TCRB |
| tr-TR | Turkish (Turkey) | TCRB geni yenien düzenlenmeler |
| ru-RU | Russian (Russian Federation) | TCRB ген перестройки |
| nl-NL | Dutch (Netherlands) | TCRB-genherschikking Synonyms: TCRB-gentranslocaties |
| fr-FR | French (France) | TCRB gène réarrangements |
| pl-PL | Polish (Poland) | TCRB gen rearanżacje Synonyms: Rearanżacje genu TCRB |
| el-GR | Greek (Greece) | Γονιδιακές αναδιατάξεις TCRB Synonyms: Γονιδιακές αναδιατάξεις TCRB |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://