LP20065-6
CD18
Active
Descriptions
Found on all leukocytes
Associated with some B-cell neoplasms
Absent in leukocyte adhesion deficiency (LAD)
Source: Regenstrief Institute
Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), also known as CD18 or ITGB2, is a human gene. CD18 is the beta subunit of three different structures: LFA-1 (paired with CD11a), Macrophage-1 antigen (paired with CD11b), Integrin alphaXbeta2 (paired with CD11c), and Integrin alphaXbeta2 (paired with CD11c). The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD18
Basic Part Properties
- Part Name
- CD18
- Part Display Name
- CD18
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-08
- Construct for LOINC Short Name
- CD18
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD18 Synonyms: Beta2; |
| es-ES | Spanish (Spain) | CD18 |
| it-IT | Italian (Italy) | CD18 |
| tr-TR | Turkish (Turkey) | CD18 |
| ru-RU | Russian (Russian Federation) | CD18 |
| nl-NL | Dutch (Netherlands) | CD18 |
| pl-PL | Polish (Poland) | CD18 Synonyms: CD18 |
| el-GR | Greek (Greece) | CD18 Synonyms: CD18 |
LOINC Copyright
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