LP20090-4
CD47
Active
Description
CD47 (Cluster of Differentiation 47) is a human protein encoded by the CD47 gene.
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [1] Isoform 2 and 4 are the most abundant. Other than thrombospondin, CD47 also binds CD172a. CD47 deficient mice have been generated. Their reported phenotype is a defect in cellular migration of the CD172a expressing cells, suggesting that CD47 to CD172a interactions are necessary for the proper distribution of these cell types.
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Source: Wikipedia,
CD47
Basic Part Properties
- Part Name
- CD47
- Part Display Name
- CD47
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-08
- Construct for LOINC Short Name
- CD47
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD47 Synonyms: CDw149; |
| es-ES | Spanish (Spain) | CD47 |
| it-IT | Italian (Italy) | CD47 |
| tr-TR | Turkish (Turkey) | CD47 |
| ru-RU | Russian (Russian Federation) | CD47 |
| nl-NL | Dutch (Netherlands) | CD47 |
| pl-PL | Polish (Poland) | CD47 Synonyms: CD47 |
| el-GR | Greek (Greece) | CD47 Synonyms: CD47 |
LOINC Copyright
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