Description

The ITGB3 gene (integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)) [HGNC Gene ID:6156] is located on chromosome 17q21.32. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Decreased expression of CD61 on platelets is associated with Glanzmann thrombasthenia, and CD61 is used as a cell marker in acute megakaryoblastic leukemia (AMKL) [provided by RefSeq, Jul 2008] [NCBI Gene ID:3690] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
CD61
Part Display Name
CD61
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-08
Construct for LOINC Short Name
CD61

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP20146-4

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)CD61
Synonyms: Beta 3;Beta 3 整合素链;Beta3;Beta-3 整合素;CD61A;GPIIb/IIIa;发现于血小板和巨核细胞之上。与急性髓系白血病 M7(AML M7)相关。
es-ESSpanish (Spain)CD61
it-ITItalian (Italy)CD61
tr-TRTurkish (Turkey)CD61
ru-RURussian (Russian Federation)CD61
nl-NLDutch (Netherlands)CD61
pl-PLPolish (Poland)CD61
Synonyms: CD61
el-GRGreek (Greece)CD61
Synonyms: CD61