Version 2.80

Description

Prolylhydroxyproline is a dipeptide. Prolylhydroxyproline is a marker of bone collagen degradation, showing high sensitivity for the diagnosis of osteoporosis. Prolylhydroxyproline has been suggested as a possible alternative to hydroxyproline determination in bone resorption studies. Prolylhydroxyproline is one of the iminodipeptides present in the urine of patients with prolidase deficiency. Prolidase (X-Pro dipeptidase EC 3.4. 13.9) splits iminodipeptides containing C-terminal proline or hydroxyproline (X-Pro or X-Hyp) to X+Pro or X+Hyp. Prolidase deficiency is a rare autosomal recessive disease characterized by chronic ulcerative dermatitis and mental retardation. These patients excrete large amounts of iminodipeptides containing C-terminal proline in the urine due to hereditary prolidase deficiency. PMID: 12636053 PMID: 11863289 PMID: 2387877 PMID: 1874885 [PMID: 9586797] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database ,

Basic Part Properties

Part Name
Prolylhydroxyproline
Part Display Name
Prolylhydroxyproline
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-10-22
Construct for LOINC Short Name
Prolyl-OH-proline

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP201689-9
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP201689-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 脯氨酰羟脯氨酸
Synonyms: 脯氨酰基羟基脯氨酸;脯氨酰基羟脯氨酸
tr-TR Turkish (Turkey) Prolilhidroksiprolin
it-IT Italian (Italy) Prolylidrossiprolina
es-ES Spanish (Spain) Prolilhidroxiprolina
nl-NL Dutch (Netherlands) prolylhydroxyproline
el-GR Greek (Greece) Προλυλ-υδροξυπρολίνη
Synonyms: Προλυλ-υδροξυπρολίνη