LP201689-9
Prolylhydroxyproline
Active
Description
Prolylhydroxyproline is a dipeptide. Prolylhydroxyproline is a marker of bone collagen degradation, showing high sensitivity for the diagnosis of osteoporosis. Prolylhydroxyproline has been suggested as a possible alternative to hydroxyproline determination in bone resorption studies. Prolylhydroxyproline is one of the iminodipeptides present in the urine of patients with prolidase deficiency. Prolidase (X-Pro dipeptidase EC 3.4. 13.9) splits iminodipeptides containing C-terminal proline or hydroxyproline (X-Pro or X-Hyp) to X+Pro or X+Hyp. Prolidase deficiency is a rare autosomal recessive disease characterized by chronic ulcerative dermatitis and mental retardation. These patients excrete large amounts of iminodipeptides containing C-terminal proline in the urine due to hereditary prolidase deficiency. PMID: 12636053 PMID: 11863289 PMID: 2387877 PMID: 1874885 [PMID: 9586797] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database,
Basic Part Properties
- Part Name
- Prolylhydroxyproline
- Part Display Name
- Prolylhydroxyproline
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-10-22
- Construct for LOINC Short Name
- Prolyl-OH-proline
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 脯氨酰羟脯氨酸 Synonyms: 脯氨酰基羟基脯氨酸; |
| es-ES | Spanish (Spain) | Prolilhidroxiprolina |
| it-IT | Italian (Italy) | Prolylidrossiprolina |
| tr-TR | Turkish (Turkey) | Prolilhidroksiprolin |
| nl-NL | Dutch (Netherlands) | prolylhydroxyproline |
| fr-FR | French (France) | Prolylhydroxyproline |
| pl-PL | Polish (Poland) | Prolylhydroksyprolina Synonyms: Prolina-hydroksyprolina; |
| el-GR | Greek (Greece) | Προλυλ-υδροξυπρολίνη Synonyms: Προλυλ-υδροξυπρολίνη |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://