Version 2.80

Description

Furoylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:. acyl-CoA + glycine < -- > CoA + N-acylglycine. Dietary studies show that 2-Furoylglycine precursors are of exogenous origin. Most probably from furan derivatives found in food prepared by strong heating. This may explain the absence of 2-furoylglycine in urine of breastfed children.[PMID 4630229] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , Furoylglycine

Basic Part Properties

Part Name
Furoylglycine
Part Display Name
Furoylglycine
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-10-31
Construct for LOINC Short Name
Furoylglycine

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 呋喃甲酰基甘氨酸
Synonyms: 糠酰甘氨酸;呋喃甲酰甘氨酸;糠酰基甘氨酸
tr-TR Turkish (Turkey) Furoyilglisin
es-ES Spanish (Spain) Furoilglicina
it-IT Italian (Italy) Furoil-glicina
nl-NL Dutch (Netherlands) furoylglycine
el-GR Greek (Greece) Φουροϋλογλυκίνη
Synonyms: Φουροϋλογλυκίνη