Version 2.78

Description

Cytochrome P450-2D6 (CYP2D6;[HGNC Gene ID: 2625]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism approximately 25% of drugs in current clinical use. Genetic variations in CYP2D6 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP2D6 and selection of alternative dosing or agents may be necessary in individuals with specific CYP2D6 genetic variations. PMID: 23486447 PMID: 24458010 PMID: 25974703. See https://www.pharmgkb.org/gene/PA128 for more information and dosing guidelines for drugs impacted by CYP2D6 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

Basic Part Properties

Part Display Name
CYP2D6 gene product metabolic activity interpretation
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-11-09
Construct for LOINC Short Name
CYP2D6 gene prod met act imp

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP202919-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) CYP2D6 基因产物新陈代谢活性解释
Synonyms: CYP2D6 基因产物新陈代谢（代谢）活性解释（说明、阐释、诠释、解释说明）
es-ES Spanish (Spain) Gen CYP2D6 interpretation de la actividad en el metabolismo de fármacos
it-IT Italian (Italy) Interpretazione dell'attività metabolica del gene CYP2D6
tr-TR Turkish (Turkey) CYP2D6 geni ürünü metabolik aktivite yorumu
nl-NL Dutch (Netherlands) CYP2D6-gen product metabole activiteit interpretatie
Synonyms: CYP2D6 gen product metabole activiteit interpretatie