Version 2.80

Description

Floxacillin or flucloxacillin (tradename Flopen or Floxapen) is an isoxazolyl penicillin often used to treat many infections caused by Gram-positive species, such as streptococci and penicillinase-producing staphylococci, including methicillin-susceptible Staphylococcus aureus (MSSA). Studies have shown that flucloxacillin is 95%-97% bound to plasma albumin. The extent of binding to plasma proteins is important, as it is the unbound (free) fraction of drug that produces the pharmacological effect. For critically ill patients, hypoalbuminaemia may be observed, and the effects of hypoalbuminaemia on the pharmacokinetics of highly bound antiboitics may pose a potential risk for inappropriate antibiotic therapy in these patients. PMID: 20530507 Source: Regenstrief LOINC , PMID: 20530507

Basic Part Properties

Part Name
Floxacillin.free
Part Display Name
Floxacillin Free
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-01-04
Construct for LOINC Short Name
Floxacillin free

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP206568-0
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP206568-0

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) Floxacillina
zh-CN Chinese (China) 氟氯西林.游离型
Synonyms: 氟氯西林（氟氯唑青霉素、氟氯苯唑青霉素、氟氯苯甲异恶唑青霉素、氟氯青霉素、氟沙星）.游离型;游离型（游离）氟氯西林（氟氯唑青霉素、氟氯苯唑青霉素、氟氯苯甲异恶唑青霉素、氟氯青霉素、氟沙星）
es-ES Spanish (Spain) Floxacilina libre
nl-NL Dutch (Netherlands) flucloxacilline.vrij
el-GR Greek (Greece) Φλοξακιλλίνη.ελεύθερη
Synonyms: Φλοξακιλλίνη.ελεύθερη