Version 2.80

Description

The projected heparin dose response test is a point-of-care test performed on fresh whole blood (no citrate added) to assess patient's individual response to heparin. The test measures the baseline (no heparin) activated clotting time, and the activated clotting times on the same blood to which 2 different concentrations of unfractionated heparin is added. From these measurements a projected dose response is calculated. This test is used in the cardiac operating room where patients are anticoagulated with high (3 to 5 units heparin/mL of blood) levels of unfractionated heparin. The effect of this level of heparin anticoagulation is measured every 20 to 30 minutes while the patient is on cardiopulmonary bypass. The heparin dose response is used to determine the appropriate amount of heparin needed to increase the patient's activated clotting time to the target level used by the hospital. The heparin dose response test is typically performed once at the beginning of the surgical procedure before the patient is placed on bypass. Once the patient is heparinized and placed on bypass the activated clotting time and the heparin concentration (whole blood heparin assay) are determined in the operating room every 20 to 30 minutes during the procedure. Heparin administered to patients in the cardiac OR is unfractionated, not low molecular weight. The amount given greatly exceeds the amount that could be monitored by the APTT. In this setting the most important concern is that the patient receive the appropriate amount in order to reach and maintain the required anticoagulant (thrombin inhibiting) protection. Source: Regenstrief LOINC

Basic Part Properties

Part Name
Projected heparin concentration to reach target ACT
Part Display Name
Projected heparin concentration to reach target ACT
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-01-04
Construct for LOINC Short Name
Proj heparin conc

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP206571-4

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) Concentrazione di eparina prevista per raggiungere il target ACT
zh-CN Chinese (China) 达到活化凝血时间的预计肝素浓度
Synonyms: 达到活化凝血时间（ACT、激活凝血时间、激活全血凝固时间）的预计（计划、推算、预测）肝素浓度;达到活化凝血时间所需的预计肝素浓度
es-ES Spanish (Spain) Concentración de heparina prevista para alcanzar el objetivo ACT
fr-CA French (Canada) Héparine concentration pour TCA cible
el-GR Greek (Greece) Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου
Synonyms: Προβλεπόμενη συγκέντρωση ηπαρίνης για την επίτευξη του ενεργοποιημένου χρόνου πήξης-στόχου