Version 2.77

Descriptions

Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Anti-nuclear antibodies

Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Display Name
Nuclear Ab
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-06-21
Construct for LOINC Short Name
ANA

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP20752-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 细胞核抗体
Synonyms: ANA;NA;抗核 Ab;抗核抗体;抗核抗体（Antinuclear antibody，ANA）;细胞核 Ab;胞核 Ab;胞核抗体
pl-PL Polish (Poland) Jądrowe Ab
Synonyms: Przeciwciała przeciwjądrowe