LP207900-4

MYH7 gene

Active

Description

The MYH7 gene (myosin, heavy chain 7, cardiac muscle, beta) [HGNC Gene ID:7577] is located on chromosome 14q12. Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4625] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name

MYH7 gene

Part Display Name

MYH7 gene

Part Type

Component (Describes the core component or analyte measured)

Created On

2016-02-28

Construct for LOINC Short Name

MYH7

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