LP208427-7
CTSK gene
Active
Description
The CTSK gene (cathepsin K) [HGNC Gene ID:2536] is located on chromosome 1q21. The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] [NCBI Gene ID:1513] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- CTSK gene
- Part Display Name
- CTSK gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-03-17
- Construct for LOINC Short Name
- CTSK
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CTSK 基因 Synonyms: 组织蛋白酶 K; |
| es-ES | Spanish (Spain) | Gen CTSK |
| it-IT | Italian (Italy) | CTSK, gene Synonyms: Gene CTSK |
| nl-NL | Dutch (Netherlands) | CTSK-gen Synonyms: CTSK gen |
| fr-FR | French (France) | CTSK gène |
| pl-PL | Polish (Poland) | CTSK gen Synonyms: Gen CTSK |
| el-GR | Greek (Greece) | Γονίδιο CTSK Synonyms: Γονίδιο CTSK |
LOINC Copyright
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