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Description

The MYD88 gene, located on chromosome 3, encodes the myeloid differentiation primary response protein MyD88. Germline mutations in MYD88 are associated with a disorder called MyD88 deficiency, which is characterized by recurrent bacterial infections. A specific somatic mutation in the MYD88 gene involving replacement of the amino acid leucine by proline at position 265 (Leu265Pro) is found in more than 90% of patients with Waldenstrom macroglobulinemia, a type of blood cancer associated with excessive production of IgM. This same mutation is also found in more than half of patients with IgM monoclonal gammopathy of undetermined significance (IgM-MGUS) as well as some patients with diffuse large B-cell lymphoma (DLBCL) and marginal zone lymphoma. [MedlinePlus Gene: MYD88] Source: Regenstrief LOINC

Basic Part Properties

Part Name
MYD88 gene
Part Display Name
MYD88 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-04-26
Construct for LOINC Short Name
MYD88

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP212147-5
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https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP212147-5

Language Variants Get Info

TagLanguageTranslation
fr-FRFrench (France)MYD88 gène
it-ITItalian (Italy)MYD88, gene
nl-NLDutch (Netherlands)MYD88-gen
es-ESSpanish (Spain)Gen MYD88
zh-CNChinese (China)MYD88 基因
Synonyms: MYD88 Innate Immune Signal Transduction Adaptor gene;MYD88 天然免疫信号转导接头蛋白（接头分子、衔接蛋白）基因
pl-PLPolish (Poland)MYD88 gen
Synonyms: Gen MYD88
el-GRGreek (Greece)Γονίδιο MYD88
Synonyms: Γονίδιο MYD88