LP212177-2

Ureidopropionate

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Description

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. PMID: 11675655 ] Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.[HMDB ID: HMDB00026] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

Basic Part Properties

Part Name

Ureidopropionate

Part Display Name

Ureidopropionate

Part Type

Component (Describes the core component or analyte measured)

Created On

2016-04-27

Construct for LOINC Short Name

Ureidopropionate

Related Codes

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