LP21316-2
Zalcitabine
Active
Descriptions
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy. Source: National Library of Medicine, MeSH 2006
Zalcitabine is a Nucleoside Reverse Transcriptase Inhibitor (NRTI) antiretroviral drug used in the treatment of HIV. Drug resistance reports assist with treatment decisions. Source: Regenstrief Institute
Zalcitabine, also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor (NARTI) sold under the trade name Hivid.
Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV infection and AIDS, but sale and distribution has been discontinued since 2006.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Zalcitabine (2'-3'-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor (NARTI) sold under the trade name Hivid. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Zalcitabine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2001-01-02
- Construct for LOINC Short Name
- Zalcitabine
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 扎西他滨 Synonyms: ddC; |
| fr-CA | French (Canada) | Zalcitabine |
| et-EE | Estonian (Estonia) | Salkitabiin |
| es-ES | Spanish (Spain) | Zalcitabina |
| it-IT | Italian (Italy) | Zalcitabina |
| tr-TR | Turkish (Turkey) | Zalcitabine |
| ru-RU | Russian (Russian Federation) | Залцитабин |
| nl-NL | Dutch (Netherlands) | zalcitabine |
| fr-BE | French (Belgium) | Zalcitabine |
LOINC Copyright
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