LP220295-2
Reticulocytes.low light scatter
Active
Description
Reticulocytes are immature red blood cells (RBCs). Measures of reticulocyte maturity can provide complementary information to absolute reticulocyte counts for assessing erythropoietic activity. As reticulocytes mature, they progressively accumulate hemoglobin and lose RNA, so maturity can be measured based on the reticulocyte RNA content. Automated analyzers can use this property to subclassify reticulocytes into different maturity groups by tagging the intracellular RNA and then measuring the light scatter (fluorescence) of the tagged cells, which is proportional to the RNA content. RBCs have the least scatter, followed by the most mature reticulocytes, mid-level, and least mature, which have the highest scatter. The immature reticulocyte fraction (IRF) is defined as the proportion of mid- and high-scatter reticulocytes out of the total. A rise in IRF is one of the earliest indicators of bone marrow engraftment or recovery from intensive chemotherapy. The IRF can also be used as an early indicator of response to erythropoietin therapy in patients with chronic renal failure and to treatment for anemia. (Hematology: Clinical Principles and Applications By Bernadette F. Rodak, George A. Fritsma Kathryn Doig, page 556) Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Reticulocytes.low light scatter
- Part Display Name
- Reticulocytes.low light scatter
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-06-27
- Construct for LOINC Short Name
- Retic.low scatter
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Reticulocitos. Luz de baja dispersión |
| zh-CN | Chinese (China) | 网织红细胞.低度光散射 Synonyms: 网织红细胞（网状红血球、 |
| it-IT | Italian (Italy) | Reticolociti.bassa diffusione della luce |
| pl-PL | Polish (Poland) | Retykulocyty, małe rozproszenie światła |
| el-GR | Greek (Greece) | Δικτυοερυθροκύτταρα.χαμηλή σκέδαση φωτός Synonyms: Δικτυοερυθροκύτταρα.χαμηλή σκέδαση φωτός |
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