Version 2.78

Description

Transcriptional intermediary factor 1-gamma (TIF1-gamma or E3 ubiquitin-protein ligase TRIM33), induces inactivation of the SMAD4 protein, which promotes cell growth (including malignant tumours) by inhibiting the anti-proliferative effects of TGF-beta. Anti-TIF1-gamma autoantibodies have been associated with adult- and juvenile-onset dermatomyositis (DM), and particularly with cancer-associated DM. PMID: 20501546 Source: Regenstrief LOINC, PMID: 20501546

Basic Part Properties

Part Display Name
TIF1-gamma
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-07-07
Construct for LOINC Short Name
TIF1-gamma

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP220413-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) TIF1-gamma
Synonyms: TIF1-γ;TIF1-gamma;转录中介因子 1-γ;转录中介因子 1-gamma;Transcriptional intermediary factor 1-gamma;E3 泛素连接酶 TRIM33;E3 ubiquitin-protein ligase TRIM33
es-ES Spanish (Spain) TIF1-gamma
it-IT Italian (Italy) TIF1-gamma
nl-NL Dutch (Netherlands) TIF1-gamma