LP229976-8
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 1
Active
Description
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1-GluA4 (also known as GluR1-GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions. PMCID: PMC4478035 The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. PMID: 23983888 The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. PMID: 24707504 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- AMPAR1
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-09-14
- Construct for LOINC Short Name
- AMPAR1
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 1 Synonyms: Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 1; |
| es-ES | Spanish (Spain) | Receptor 1 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato |
| it-IT | Italian (Italy) | Recettore tipo 1 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato Synonyms: AMPAR1 |
| nl-NL | Dutch (Netherlands) | alfa-amino-3-hydroxy-5-methyl-4-isoxazolpropionaatreceptor 1 |
LOINC Copyright
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