LP232473-1
Nuclear pore protein gp210 Ab.IgG
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Reference Information
| Type | Source | Reference |
|---|---|---|
| Article | Regenstrief LOINC | Nuclear pore complex (NPC) gp210 is a type I integral membrane protein that binds NPCs to the pore membrane. IgG autoantibodies to gp210 are present in 22-32% of patients with primary biliary cirrhosis (PBC), an autoimmune disease that progressively destroys intrahepatic biliary epithelial cells. The gp210 IgG antibodies predominantly bind to a 15-amino acid portion of the C-terminal domain of gp210. Studies have shown that the presence of gp210 antibodies in patients with PBC predicts more severe disease and a worse prognosis. PMID: 22487189 Link |
Basic Part Properties
- Part Name
- Nuclear pore protein gp210 Ab.IgG
- Part Display Name
- Nuclear pore protein gp210 IgG
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-11-14
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| fr-FR | French (France) | Pore nucléaire proteine gp210 anticorps IgG |
| pl-PL | Polish (Poland) | Białko porów jądrowych gp 210 Ab.IgG Synonyms: Przeciwciała IgG do białka porów jądrowych gp-210 |
LOINC Copyright
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