LP247698-6
clozapine N-oxide
Active
Description
Clozapine is a drug used for the treatment of schizophrenia. It does not produce significant effects to the extrapyramidial nerves like other neuroleptics and is often effective in patients who were previously resistant to other types of schizophrenia medications. The primary active metabolites of clozapine are norclozapine and clozapine N-oxide. The average half-life of the N-oxide metabolite in plasma has been observed at 8.6 hours, lower than norclozapine which was observed at 19.2 hours and clozapine at 10.5 hours after which the drugs are excreted in urine via the kidneys.
[WOL: doi/10.1177/00912709922008245/epdf]
Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- clozapine N-oxide
- Part Display Name
- clozapine N-oxide
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-12-27
- Construct for LOINC Short Name
- CNO
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Clozapina-N-óxido |
| zh-CN | Chinese (China) | 氯氮平 N-氧化物 Synonyms: N-氧化氯氮平; |
| it-IT | Italian (Italy) | Clozapina N-ossido |
| nl-NL | Dutch (Netherlands) | clozapine-N-oxide |
| fr-FR | French (France) | N-oxyde clozapine |
| el-GR | Greek (Greece) | Ν-οξείδιο της κλοζαπίνης Synonyms: Ν-οξείδιο της κλοζαπίνης |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://