Version 2.78

Description

M3 muscarinic acetylcholine receptors (M3R) are part of the rhodopsin-like G-protein coupled receptor family. They are present on many tissues throughout the body and control the effects of acetylcholine in the central and peripheral nervous system as well as have an impact on physiological functions including the airway, eye and intestinal smooth muscle contraction, heart rate and glandular secretions. (M3R) is one of five muscarinic acetylcholine receptor subtypes and is located in smooth muscles, endocrine glands, exocrine glands, lungs, pancreas and the brain. The M3R influences exocrine secretion including saliva.[UniProt: P20309] Antibodies that inhibit M3R have been found in patients with Sjögren's syndrome (SS). SS is an autoimmune disease that involves an autoimmune attack against the salivary and lacrimal glands. [PMID: 23629427] A negative result for M3R antibody does not rule out myasthenia gravis. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Muscarinic acetylcholine receptor M3
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-12-29
Construct for LOINC Short Name
Muscarinic AChR M3

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP247723-2

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Receptor M3 muscarínico de acetilcolina
zh-CN Chinese (China) 毒蕈碱型乙酰胆碱受体 M3
Synonyms: 蕈毒碱型乙酰胆碱受体 M3;m3 mAChR
it-IT Italian (Italy) Recettore muscarinico acetilcolina M3
nl-NL Dutch (Netherlands) muscarine-acetylcholinereceptor M3