Version 2.77

Description

Lefamulin is an antibiotic in the pleuromutilin class and inhibits bacterial protein synthesis by selectively binding to the ribosomal peptidyl transferase center and interfering with peptide transfer. It can be administered orally and intravenously and is effective against respiratory and skin pathogens, including Staphylococcus and Streptococcus species, gram-negative organisms such as Haemophilus influenzae, and atypical respiratory pathogens such as Mycoplasma and Chlamydophila pneumoniae and Legionella pneumophila. As of early 2017, lefamulin is being studied in phase 3 clinical trials. PMID: 27161634 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Lefamulin
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-01-12
Construct for LOINC Short Name
Lefamulin

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP247819-8

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Lefamulin
zh-CN Chinese (China) 来法莫林
Synonyms: 截短侧耳素类抗生素;短截北风菌素类抗生素;乐伐沐林;CAS 1061337-51-6;pleuromutilins天然产物的衍生物;2-[[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]thio]acetic acid;(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl e
it-IT Italian (Italy) Lefamulin
nl-NL Dutch (Netherlands) lefamuline