Version 2.78

Description

Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. PMID: 19246801 -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Bacterial beta-lactam resistance ESBL blaBEL gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-02-21
Construct for LOINC Short Name
ESBL blaBEL gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP248299-2

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) gen bacteriano ESBL blaBEL resistente a beta-lactámicos
zh-CN Chinese (China) 细菌 beta-内酰胺耐药 ESBL blaBEL 基因
Synonyms: 细菌 beta-内酰胺（β-内酰胺）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） ESBL（超广谱β-内酰胺酶） blaBEL 基因
it-IT Italian (Italy) Resistenza batterica beta-lactamica, gene ESBL blaBEL
Synonyms: Gene ESBL blaBEL di resistenza batterica beta-lactamica
nl-NL Dutch (Netherlands) bacteriële bètalactamresistentie ESBL blaBEL-gen
Synonyms: bacterieel beta-lactam resistentie ESBL blaBEL gen