LP250855-6
Golimumab
Active
Description
Golimumab (GLM) is a fully human monoclonal antibody that binds with tumor necrosis factor alpha (TNF-α) and is used to treat patients with severe to moderate active rheumatoid arthritis, patients with active and progressive psoriatic arthritis alone or with methotrexate, and patients with active ankylosing spondylitis whose response to other therapies has been insufficient. TNFα is a pro-inflammatory cytokine that produces fever, inflammation, tissue destruction, and possibly shock and death. GLM differs from other TNF-α inhibitors in that it combines with both the transmembrane and soluble forms of TNF-α. GLM is administered once a month compared to the other TNF-α inhibitors that require dosing twice a week or every two weeks. The safety of using GLM is comparable to other TNF-α inhibitors which as a class have an increased risk of opportunistic infections, lymphoma and reactivation of latent tuberculosis. PMID: 20694072 PMID: 10936147 PMID: 20200692 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Golimumab
- Part Display Name
- Golimumab
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-05-09
- Construct for LOINC Short Name
- Golimumab
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 戈利木单抗 Synonyms: 高利单抗; |
| es-ES | Spanish (Spain) | Golimumab |
| it-IT | Italian (Italy) | Golimumab |
| nl-NL | Dutch (Netherlands) | golimumab |
| el-GR | Greek (Greece) | Γολιμουμάμπη Synonyms: Γολιμουμάμπη |
LOINC Copyright
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