LP262441-1
Cytolethal distending toxin B
Active
Description
Cytolethal distending toxin B (CdtB) is a protein that is produced by gram negative bacteria. CdtB targets eukaryotic DNA. PMID: 16427513 Antibodies against this toxin can cross react with vinculin, a cytoskeletal protein found in epithelial cells. In animal models, these vinculin antibodies have been shown to cause symtoms similar to irritable bowel syndrome (IBS). CdtB antibodies are useful as biomarkers for irritable bowel syndrome with diarrhea (D-IBS) in humans, and may help distinguish D-IBS from inflammatory bowel disease in the workup of chronic diarrhea. PMID: 25970536 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Cytolethal distending toxin B
- Part Display Name
- Cytolethal distending toxin B
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-07-13
- Construct for LOINC Short Name
- CdtB
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Cytolethal distending toxin B |
| es-ES | Spanish (Spain) | toxina B de Cytolethal distending |
| zh-CN | Chinese (China) | 细胞致死膨胀毒素 B Synonyms: 细菌细胞致死性膨胀毒素; |
| fr-FR | French (France) | Toxine cytoléthale B |
| el-GR | Greek (Greece) | Κυτταρολεθρική διογκούμενη τοξίνη Β Synonyms: Κυτταρολεθρική διογκούμενη τοξίνη Β |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://