Description

A polymerase chain reaction (PCR) assay using nox-specific restriction fragment length polymorphisms (RFLPs) has been developed that can differentiate all five species of porcine Brachyspira. PMID: 12089283 The nox gene encodes NADH oxidase in Brachyspira species. Species of Brachyspira can be differentiated based on the nox gene sequence due to its variability across species. PMID: 26458507 Several species of the gram-negative spirochete Brachyspira can cause swine dysentery (SD) including B. hyodysenteriae, B. intermedia, B. innocens, B. murdochii, B. aalborgi, B. alvinipulli, B. suanatina, and a provisional species called Brachyspira hampsonii. B. hyodysenteriae, B. suanatina, and B. hampsonii cause a severe mucohaemorrhagic colitis found mainly in grower and finisher pigs. Brachyspira that are weakly heamolytic causing a mild colitis include B. murdochii, B. intermedia, B. aalborgi, and B. alvinipulli in pigs, chickens and humans. Transmission of Brachyspira sp can occur in several ways including: pigs that have subclinical infection; infection from birds or feral animals that act as potential reservoirs; reduced immunity in a herd; routine diagnostic and control measures are not adhered to; and environmental changes such as a change in diet, co-infections and other stresses that increase norepinephrine levels in the gut that can result in the growth and colonization of some species of Brachyspira. Diagnoses of Brachyspira species are primarily made using polymerase chain reaction (PCR) test and/or immune staining. PMID: 11015363 https://porcinehealthmanagement.biomedcentral.com/articles/10.1186/s40813-015-0002-1 PMID: 27629903 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Brachyspira sp nox gene
Part Display Name
Brachyspira sp nox gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-07-19
Construct for LOINC Short Name
Brachyspira sp nox gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP262511-1

Language Variants Get Info

TagLanguageTranslation
it-ITItalian (Italy)Brachyspira sp, gene nox
zh-CNChinese (China)短螺旋体属 nox 基因
Synonyms: 短螺旋体属(蛇形螺旋菌、蛇形螺旋菌属、短螺旋体) nox 基因
es-ESSpanish (Spain)Gen nox Brachyspira sp
fr-FRFrench (France)Brachyspira gène nox
nl-NLDutch (Netherlands)Brachyspira sp. nox-gen
pl-PLPolish (Poland)Brachyspira sp nox gen
Synonyms: Gen nox Brachyspira sp
el-GRGreek (Greece)Γονίδιο Brachyspira sp nox
Synonyms: Γονίδιο Brachyspira sp nox