LP263532-6
Rotavirus C VP7 gene
Active
Description
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus C has been the cause of periodic outbreaks of infection in piglets, children, and adults, resulting in gastroenteritis and death. Group C rotavirus were initially discovered in the 1980s in swine, but were later identified in humans, cows, ferrets, and dogs. PMID: 2556635http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Rotavirus C VP7 gene
- Part Display Name
- Rotavirus C VP7 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-09-20
- Construct for LOINC Short Name
- RVC VP7
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen VP7 rotavirus C |
| it-IT | Italian (Italy) | Rotavirus c, gene VP7 |
| zh-CN | Chinese (China) | 轮状病毒 C VP7 基因 Synonyms: 轮状病毒（ROTAV、 |
| fr-FR | French (France) | Rotavirus C gène VP7 |
| nl-NL | Dutch (Netherlands) | Rotavirus C VP7-gen |
| pl-PL | Polish (Poland) | Rotawirus C gen VP7 Synonyms: Gen VP7 Rotawirusa C |
| el-GR | Greek (Greece) | Γονίδιο ροταϊού C VP7 Synonyms: Γονίδιο ροταϊού C VP7 |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://