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Description

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family of proteins, which are involved in physiologic processes including cell growth and differentiation, and embryonic development. FGF21 is involved in energy regulation and has been associated with weight loss and decreased triglyceride accumulation in the liver. In humans, fructose ingestion has been associated with an increase in circulating FGF21, and obesity may lead to FGF21 resistance. In contrast, in animal studies, increased levels of FGF21 have been found with fasting and ketogenic diets. The N-terminus of FGF21 binds to the FGF receptor and the C-terminus binds to a co-receptor; therefore, the intact form of FGF21 must be present for FGF receptor activation because binding at both sites is required. PMID: 26654352 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Fibroblast growth factor 21.intact
Part Display Name
Fibroblast growth factor 21.intact
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-10-12
Construct for LOINC Short Name
FGF-21.intact

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP263758-7

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)Factor de crecimiento de fibroblastos 21. intacto
it-ITItalian (Italy)Fibroblasto 21, fattore di crescita.intatto
zh-CNChinese (China)成纤维细胞生长因子 21.完整型
Synonyms: FGF-21.完好型;FGF-21.完整型;完好型 FGF-21;完好型成纤维细胞 GF 21;完好型成纤维细胞生长因子 21;完好型纤维母细胞 GF 21;完好型纤维母细胞生长因子 21;完整型 FGF-21;完整型成纤维细胞 GF 21;完整型成纤维细胞生长因子 21;完整型纤维母细胞 GF 21;完整型纤维母细胞生长因子 21;成纤维细胞 GF 21.完好型;成纤维细胞 GF 21.完整型;成纤维细胞生长因子 21.完好型;纤维母细胞 GF 21.完好型;纤维母细胞 GF 21.完整型;纤维母细胞生
fr-FRFrench (France)FGF-21 intact
pl-PLPolish (Poland)Czynniki wzrostu fibroblastów 21.peptyd aktywny
el-GRGreek (Greece)Αυξητικός παράγοντας ινοβλαστών 21.άθικτος
Synonyms: Αυξητικός παράγοντας ινοβλαστών 21.άθικτος